On July 31, 2025, NK Varaždin played a match against Santa Clara in the UEFA Europa League. The match took place at Estádio de São Miguel, where Varaždin unfortunately suffered a defeat with a score of 2-0. The first goal was scored by Vinícius Lopes in the 5th minute, and the second goal was added by Gabriel Silva in the 68th minute. NK Varaždin had several opportunities but failed to convert their chances. Tomislav Duvnjak and Ivan Mamut received yellow cards, which further complicated the situation for the team. In the first half, NK Varaždin had 47% ball possession, but Santa Clara had more shots on goal. This defeat poses a challenge for NK Varaždin, who must focus on upcoming matches to improve their performance in the Europa League.